This prospective study aimed to explore the effect of different pulse durations on the clinical efficacy and the adverse effects of laser-assisted hair removal using the 755 nm alexandrite laser system.įor the purpose of the study, a detailed history in regards to the onset of hirsutism and its rate of progression, a family history, a past medical history, a drug history and any sign of polycystic ovary syndrome (PCOS) or other forms of hormonal dysfunction were obtained from each patient in the first session. Therefore, rationally, the ideal should be something between these two values. The TRT for the epidermis is determined to be 3-10 milliseconds in previous studies, while this value for the hair follicle, depending on its diameter, is about 10-40 milliseconds. The pulse duration (or pulse width) must be long enough for the epidermal melanin to throw away the heat and therefore be safe regarding thermal injury, but short enough to keep adequate energy in the hair follicle to destroy it. Many studies have been conducted to examine the impact of different spot sizes and fluences on clinical improvement and the side effect profile of various hair removal lasers, 7- 9 but as far as we know, there are not too many studies for the examination of the outcome of treatment using different pulse durations, although this parameter has been shown to be important. Selective thermal damage of these targets happens when sufficient energy density at a given wavelength which is superiorly absorbed by the chromophore, is released at a time period not longer than the thermal relaxation time (TRT) of the target. The main targets regarding hair removal laser treatment appear to be the dermal papilla and the bulge. 5 An astute clinician with a precise selection of these parameters can produce desired tissue injuries confined to the chromophore. 4 Each of the pulsed light sources generates different pulse durations, spot sizes and fluences that provide varying clinical responses. The rate and extent of this heat are determined by the fluence and the duration of exposure. Melanin, the natural chromophore of these types of lasers, absorbs the laser light and transforms energy into heat. In fact, the invention of these instruments has been a revolution in the hair removal industry, with many different laser systems currently available. Over the past decade, hair removal lasers have been used widely for long-term hair reduction and their technology has advanced very fast. Unwanted hair growth which is seen in some pathologic situations such as hypertrichosis or hirsutism is one of the most common complaints among patients of dermatology clinics. There was not any significant difference in clinical efficacy or the side effect profile.Ĭonclusion: Using a 755 nm alexandrite laser for hair removal is an effective and safe method for delaying hair regrowth and this delay is not markedly different by increasing the pulse duration from 3 to 10 milliseconds. Results: one month after the laser treatment, the clearance rate was 56% with both 3 and 10 milliseconds pulse durations. Photographs were taken and hair counts were checked before the treatment and one month postoperatively. Methods: Fifty female patients with facial hirsutism were subjected to a hair removal procedure with an alexandrite laser, using 3 and 10 milliseconds pulse durations on each side of the face every 5 weeks for three sessions. This study aimed to investigate the effectiveness of hair removal using an alexandrite laser with different pulse durations. However, little is known about the effect of varying the pulse duration on clinical results and side effects. Introduction: Laser-assisted hair removal is widely used by a large number of patients complaining of unwanted hair.
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